NEW ORLEANS, La. – The New Orleans Saints ride a five-game winning streak into their matchup with the injury-ravaged San Francisco 49ers in the Superdome.
The Niners are missing numerous top players including quarterback Jimmy Garoppolo as they return to the site of a wild 48-46 victory in 2019 that helped propel San Francisco to an NFC title.
Now the 49ers are 4-5 and the 22nd defending conference champion to have a losing mark through nine games.
Just three such teams have rebounded with make the playoffs.
Saints QB Drew Brees passed for four TDs in a 38-3 victory at Tampa Bay last week.